📢 Dr. Bikman’s Coaching Site, Insulin IQ: https://insuliniq.com and/or 📢 Become an Insider, Ben’s website: https://www.benbikman.com In this Metabolic Classroom lecture, Dr. Bikman breaks down the true nature and benefits of creatine—a molecule often misunderstood as merely a muscle-building supplement. Creatine plays a critical role in cellular energy production by helping regenerate ATP, especially in high-energy tissues like skeletal muscle and the brain. While our bodies produce creatine endogenously, supplementation can significantly enhance its availability and effects. Ben discusses how creatine has been shown to improve physical performance, support brain health, and even influence glucose metabolism. It helps increase strength, power output, and recovery during resistance training. In the brain, it supports cognitive function and may protect against neurodegenerative conditions. For individuals with insulin resistance or type 2 diabetes, creatine can improve glucose uptake by enhancing GLUT4 translocation. He also addresses common myths—especially the misconception that creatine damages the kidneys. Ben emphasizes that while creatinine levels may rise with supplementation, this does not indicate harm in healthy individuals. He further explains the potential gene-level benefits of creatine, such as improved expression of IGF-1 and myogenic regulatory factors related to muscle health. The lecture concludes with practical advice on dosing and choosing the right form of creatine, noting that creatine monohydrate remains the most effective and well-studied option. Ben encourages its use not just for athletes but for anyone looking to support muscle, brain, or metabolic health. Show Notes/References: For complete show notes and references, we invite you to become an Insider subscriber. You’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben after the lecture, ad-free podcast episodes, show notes and references, online Office Hours access, Ben’s Research Review Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more: https://www.benbikman.com Translation Notes: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.) In addition, our channel has first access to YouTube’s new, innovative “auto-dubbing” feature. The process currently supports translations from English into many languages, with more to come. Click on the gear icon, then choose “Audio track” to access. #Creatine #BenBikman #MetabolicHealth #ATP #InsulinResistance #BrainHealth #MuscleRecovery #CreatineMonohydrate #CognitivePerformance #EnergyMetabolism #GlucoseControl #Neuroprotection #MitochondrialHealth #SarcopeniaPrevention #Type2Diabetes #Nootropics #SupplementScience #KidneyHealth #MuscleGrowth #HealthOptimization Timestamps (approximate): 1:01 – What is creatine and why is it important? 2:02 – Creatine’s energy buffering mechanism 5:08 – How the body makes and gets creatine 6:13 – Dietary sources and vegetarians’ disadvantage 7:06 – Supplement types and dosing strategies 10:03 – Creatine for muscle power, recovery, and performance 12:17 – Brain health benefits and cognitive effects 14:39 – Creatine and glucose control 16:40 – Lesser-known cellular benefits: membranes, oxidative stress, gene expression 21:04 – Debunking the kidney myth 24:14 – Supplement recommendations and populations who benefit Ben’s favorite yerba maté and fiber supplement: https://ufeelgreat.com/usa/en/c/1BA884 Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10) Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20) Ben’s favorite health check-up for women: https://choosejoi.co/drben15 (discount: DRBEN15) Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15) Ben’s favorite exogenous ketone: https://ketone.com/BEN30 (discount: BEN30) Other products Ben likes: https://www.amazon.com/shop/benbikmanphd